猴头菌转化EGB发酵液提取物抗氧化及抑制非酶糖基化活性研究

猴头菌转化银杏叶粗提物发酵液具有清除体外自由基及抑制体外非酶糖基化反应的作用，对四氧嘧啶诱导的糖尿病模型小鼠具有显著的降血糖效果。但由于发酵液成分复杂，有效成分含量低，不便于直接服用，因而有必要对发酵液功能成分进行提取。笔者以抗氧化活性、体外非酶糖基化反应为指标，比较了、猴头菌转化EGB发酵液经AB-8吸附前后活性物质的活性变化，以期为发酵液的分离提取及提取产物的利用提供参考。

Study on Anti-oxidation and Inhibitory Effect on Nonenzymatic Glycation Reaction of Fermentation Extract from Biotransformation of Ginkgo biloba L. (EGB) by Hericium erinaceus

[Objective] In order to study the anti-oxidation and inhibitory effect on nonenzymatic glycation reaction of EGB fermentation extraction bio-transformed by Hericium erinaceus. [Method] The free radical scavenging ability and reducing capacity of DPPH as well as inhibitory rate of nonenzymatic glycation reaction were measured targets for comparing changes of anti-oxidation and inhibitory effect on nonenzymatic glycation reaction of fermentation ly-ophilizer and fermentation extraction before and after EGB fermention adsorbed by AB-8 macroporous resin. The EGB fermention was biotransformed by He-ricium erinaceus. [Result]After adsorbed by AB-8 macropous resin,the bioactive matters were concentrated and separated. The free radical scavenging rate, reducing capacity and inhibitory rate of nononzymatic glycation reaction were increased significantly after adsorbed by AB-8 macroporons resin. [Con-dusion] AB-8 macroporous resin could be used for preliminary concenuation of EGB fermentation which was biotransfonned by Hericium erinaceus.