Proliferative responses of lymphocytes to mitogens in the gray, short-tailed opossum, Monodelphis domestica. |
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| Authors: | C M Brozek E W Kaleta D F Kusewitt R D Ley |
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| Affiliation: | Photomedicine Program, Lovelace Medical Foundation, Albuquerque, NM 87108. |
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| Abstract: | A South American opossum (Monodelphis domestica) is a model animal for studies on the health effects of exposure to ultraviolet radiation (UVR). As part of a broad evaluation of immune function in this animal, we have tested in vitro mitogenic responses using whole blood cultures. Lymphocytes proliferated in the presence of phytohemagglutinin (PHA), concanavalin A (Con A), and pokeweed mitogen (PWM), but were unresponsive to bacterial lipopolysaccharide (LPS). |
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