Field Distribution of END Phenomenon-Negative Bovine Viral Diarrhea
Virus |
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| Authors: | Kaoru NISHINE Hiroshi AOKI Yoshihiro SAKODA Akio FUKUSHO |
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| Institution: | 1)School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan;2)Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, North 18, West 9, Kita-ku, Sapporo 060-0818, Japan |
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| Abstract: | Field isolates of BVDV which do not show the exaltation of Newcastle disease virus (END)
phenomenon (END–) are rarely reported. In this study, 45 BVDV field isolates
from cattle in Hokkaido prefecture in Japan were analyzed by the reverse plaque formation
method, the END method and observation of cytopathic effects. END– virus was
detected in 34 of 45 isolates (75.6%), although 35 of 45 field isolates contained END
phenomenon positive virus as the predominant virus population. We propose that
END– viruses are widely distributed in the field and that it is possible that
the mixture of biologically distinct BVDV correlates with the appearance of disease in
infected animals. |
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| Keywords: | bovine viral diarrhea virus END phenomenon pestivirus quasispecies reverse plaque formation |
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