The efficacy and safety of cefovecin in the treatment of feline abscesses and infected wounds |
| |
Authors: | Stegemann M R Sherington J Passmore C |
| |
Institution: | Veterinary Medicine Research & Development, Pfizer Ltd, Sandwich, Kent CT13 9NJ, UK. |
| |
Abstract: | OBJECTIVES: To determine the efficacy and safety of cefovecin for the treatment of bacterial abscesses and wounds in cats at clinics in Germany, France, Spain and the UK. METHOD: Cats with abscesses or wounds were enrolled. Cats (217) were randomised to treatment with either cefovecin administered by subcutaneous injection at 14 day intervals or amoxicillin/clavulanic acid as twice-daily oral tablets for 14 days. Treatment courses were repeated at 14 day intervals, when deemed necessary. Clinicians assessing lesions were masked to treatment allocation. Only animals with a confirmed pretreatment bacterial pathogen were included in the efficacy analysis. Cases were evaluated 28 days after initiation of the final course of treatment. RESULTS: Cefovecin was as efficacious as amoxicillin/clavulanic acid, and efficacy was 100 per cent for both treatments. CLINICAL SIGNIFICANCE: Cefovecin, administered as a single subcutaneous injection repeated at 14 day intervals as required, was shown to be as efficacious as oral amoxicillin/clavulanic acid in the treatment of abscesses/wounds in cats. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|