水杨酸治疗奶牛蹄皮炎效果评价

目的探讨水杨酸治疗奶牛蹄皮炎的效果。方法选取45只蹄皮炎患病奶牛,对其进行随机分组,其中,5只为阴性对照组,不给予治疗措施;20只为抗菌药物对照组,给予林可霉素进行治疗;20只为水杨酸治疗组,给予40%水杨酸软膏。分别于给药第0、3、14、30天对奶牛进行跛行评分与皮肤疼痛评分并记录结果,对治疗效果进行评价。结果在给药第3天时,抗菌药物对照组和水杨酸治疗组都没有出现痊愈的病例,经过治疗后跛行程度明显减轻。给药第14天时,水杨酸治疗组的治愈率为45%,明显高于抗菌药物对照组（25%）;治疗有效率为75%,高于抗菌药物对照组（60%）。给药第30天时,水杨酸治疗组的有效率为65%,高于抗菌药物对照组（55%）。结论水杨酸临床治疗效果较好,可以作为治疗奶牛蹄皮炎的药物使用。

Therapeutic Effect of Salicylic Acid on Pododermatitis in Dairy Cow

Objective]To assess the therapeutic effect of salicylic acid on pododermatitis in dairy cow. Method]A total of 45 dairy cows clinically diagnosed as pododermatitis were selected and randomly assigned into the following three groups a negative control group （n=5） received no treatment, an antimicrobial control group （n=20） received administration of lincomycin, and a salicylic acid treatment group （n=20） received 40% salicylic acid ointment. To evaluate the therapeutic effect, the dairy cows were subjected to lameness scoring and skin pain scoring on the 0, 3^rd, 14^th, and 30^th day of the administration, respectively.Result]On the 3^rd day of administration, no fully recovered cases were observed in the antimicrobial control group and salicylic acid treatment group, and the symptom of lameness was obviously alleviated after treatment. On the 14^th day of administration, the cure rate of salicylic acid treatment group was 45%, which was obviously higher than that of the antimicrobial control group （25%）, and the effective rate was 75%, which was higher than that of the antimicrobial control group （60%）. On the 30^th day of administration, the effective rate of salicylic acid treatment group was 65%, which was higher than that of the antimicrobial control group （55%）.Conclusion]Salicylic acid has a good clinical therapeutic effect and can be used as alternative medicine for the treatment of pododermatitis in dairy cow.