Idiopathic localized eosinophilic synovitis in a cat |
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Authors: | Silverstein Deborah C Almy Frederick S Zinkl Joseph G Christopher Mary M |
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Institution: | Veterinary Medical Teaching Hospital, University of California, Davis.;Department of Pathology, Microbiology, and Immunology, University of California, Davis. |
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Abstract: | Abstract: A 4-year-old male castrated Seal Point Himalayan cat was presented for evaluation of right thoracic limb lameness of 6 weeks duration. Synovial fluid analysis of the swollen right carpal joint revealed a mixed cell synovitis, with a total nucleated cell count of 13,200/μL and 34% eosinophils. A diagnosis of idiopathic localized eosinophilic arthritis was made. Additional clinical and diagnostic findings included mild lym-phadenopathy with lymphoid hyperplasia and an antinuclear antibody titer of 1:320. Lack of multisystem involvement made systemic lupus erythematosis unlikely. Immunosuppressive therapy with oral prednisone alleviated the lameness. Eosinophilic synovitis has not previously been reported in cats. An immune-mediated mechanism was likely in this case; however, the exact etiology remains unknown. |
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Keywords: | Eosinophil eosinophilic synovitis feline immune-mediated arthritis synovial fluid |
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