Ryegrass Staggers: The Presence of Lolitrem Neurotoxins in Perennial Ryegrass Seed |
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| Authors: | RT Gallagher AG Campbell AD Hawkes PT Holland DA McGaveston EA Pansier |
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| Institution: | Ruakura Agricultural Research Centre Ministry of Agriculture and Fisheries , Private Bag, Hamilton |
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| Abstract: | Abstract Extract Sir:- Recently, two potent neurotoxins named lolitrem A and lolitrem B were isolated from herbage collected from pastures on which the livestock disorder ryegrass staggers (RGS) occurred. et al.(1) Gallagher, R.T., White, E.P. and Mortimer, P.H. 1981. Ryegrass staggers: Isolation of potent neurotoxins lolitrem A and lolitrem B from staggers-producing pastures. N.Z. vet. J., 29: 189–190. Taylor &; Francis Online], Web of Science ®] , Google Scholar] We now wish to report that samples of perennial rygrass (Loliun yeretzrze L.) seed obtained from several locations in New Zealand contained potent neurotoxins which include lolitrem A and lolitrem B. Further, when pellets made from lolitrem neurotoxin-containing seed were fed to sheep, symptoms indistinguishable from those of severe, natural RGS were induced in four sheep, and mild symptoms in three sheep. |
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