Onset of protection from experimental infection with type 2 bovine viral diarrhea virus following vaccination with a modified-live vaccine |
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Authors: | Brock K V Widel P Walz P Walz H L |
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Institution: | Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849, USA. |
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Abstract: | The onset of protection after the administration of a modified-live bovine viral diarrhea virus (BVDV) vaccine was determined. Protection was determined following experimental infection with a virulent type-2 BVDV (strain 1373) in cattle vaccinated 3, 5, or 7 days before BVDV infection. Protection, as measured by reduced virus shedding, lack of leukopenia, reduction in viremia, and reduced mortality, was present as early as 3 days after vaccination with a single dose of modified-live BVDV vaccine. Complete protection was obtained in cattle vaccinated 5 or 7 days before BVDV experimental infection. |
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