Comment on "Maternal oxytocin triggers a transient inhibitory switch in GABA signaling in the fetal brain during delivery" |
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| Authors: | Carbillon Lionel |
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| Institution: | Department of Obstetrics and Gynecology, Assistance Publique-H?pitaux de Paris, Paris 13 University, H?pital Jean Verdier, Avenue du 14 Juillet, 93143 Bondy Cedex, France. lionel.carbillon@jvr.aphp.fr |
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| Abstract: | Tyzio et al. (Reports, 15 December 2006, p. 1788) reported that maternal oxytocin triggers a transient excitatory-to-inhibitory switch of gamma-aminobutyric acid (GABA) signaling during labor, thus protecting the fetal rat brain from anoxic injury. However, a body of evidence supports the possibility that oxytocin is released from the fetal pituitary during delivery, not only from the mother, particularly under conditions of hypoxic stress. |
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