Indirect magnetic resonance lymphography of the head and neck of dogs using Gadofluorine M and a conventional gadolinium contrast agent: A pilot study |
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| Authors: | Monique N Mayer Susan L Kraft Daniel S Bucy Cheryl L Waldner Kirsten M Elliot Sheldon Wiebe |
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| Institution: | Department of Small Animal Clinical Sciences (Mayer, Elliot) and Department of Large Animal Clinical Sciences (Waldner), 52 Campus Drive, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4; Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523-1681, USA (Kraft, Bucy); Department of Medical Imaging, 103 Hospital Drive, University of Saskatchewan, Saskatoon, Saskatchewan S7N 0W8 (Wiebe). |
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| Abstract: | The purpose of this pilot study was to evaluate lymph node enhancement with an indirect magnetic resonance (MR) lymphography technique using 2 different contrast agents in the head and neck region of healthy dogs. Five dogs were imaged at various times after intradermal injection of gadoversetamide and Gadofluorine M (minimum of 1 week apart) in the right and left mandibular, temporal, and lateral neck regions. We observed consistent progressive enhancement with time in the mandibular, retropharyngeal, and superficial cervical lymph nodes. The node enhancement was comparable for both contrast agents. Contrast enhancement of the parotid lymph nodes was not seen. We conclude that this technique of indirect MR lymphography using either agent could be used to identify those lymph nodes at highest risk of metastatic disease in dogs with cancer, and to guide staging and treatment. |
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