流感病毒基因组结构及其编码蛋白研究进展

由流感病毒引起的流感是严重危害人类和畜禽健康的一种传染病。此病的暴发给世界上许多国家和地区造成了巨大的经济损失。对流感病毒基因组结构及其编码蛋白质的研究有助于进一步加强对流感的治疗和预防。流感病毒含 8个负链单股独立的 RNA片段 ,共编码1 0种蛋白。每种蛋白具有不同的结构和功能。文章主要对流感病毒不同基因片段的结构特征及其编码的结构蛋白及非结构蛋白的形态结构、功能、免疫学特性等方面的分子生物学最新研究进展进行了综述

Research Progress in Genomic Structures and Proteins of Influenza virus

Influenza is an infectious disease that can threat human health and animal husbandry seriously and has caused great economic losses in the past years. The studies on the genomic structures and proteins of influenza virus are helpful to enhance the therapy and prevention of the influenza. The pathogens of the influenza is influenza virus, whose genome is segmented, composed of eight pieces of single stranded negative sense RNA.Viral genome code for 10 proteins, each of which has important function. The paper focused on the research advances in the genomic structure characters of influenza virus and the morphostructure, immunological characters, functions of the viral structural and nonstructural proteins.