Critical illness-related corticosteroid insufficiency in a dog with septic shock |
| |
Authors: | Jamie L. Peyton DVM Jamie M. Burkitt DVM DACVECC |
| |
Affiliation: | Department of Surgical and;Radiological Sciences, William R. Pritchard Veterinary Medical Teaching Hospital, University of California Davis, Davis, CA. |
| |
Abstract: | Objective – To describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock. Case Summary – A dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI. New or Unique Information Provided – This case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog. |
| |
Keywords: | aspiration pneumonia critical care endocrinology hypotension systemic inflammatory response syndrome |
|