多糖与肠道菌群的相互作用

多糖广泛存在于动物、植物及微生物中,具有多种生理活性,是一类重要的功能成分。多糖难以被人体直接消化吸收,需经肠道菌群降解后被吸收并产生活性,反过来,多糖可通过调节肠道菌群,保护肠黏膜屏障,增加短链脂肪酸的含量发挥其益生元作用,维持人体健康或有助疾病治疗。本文将关注多糖与肠道菌群的相互作用,为多糖的益生元作用研究提供参考。

The Interplay between Polysaccharide and Gut Microbiota

Polysaccharides widely exist in animals, plants and microorganisms, and have important physiological activities. However, polysaccharide is one kind of ingredient that hard to digest. Polysaccharide is fermented by gut microbiota and then generate pharmacological activities. It was verified that polysaccharide plays probiotic role by regulate the intestinal flora, protect the intestinal mucosa barrier and increase short chain fatty acids. In this review, we focus on the interaction between polysaccharide and gut microbiota, and expect it can benefit to future research.