S‐100 Protein‐Positive Mast Cells in Canine Paranal Sinus (Sinus paranalis)

The aim of this study was to establish the immunocytochemical expression of S‐100 protein in mast cells, localized in the wall of dog's paranal sinus. Control serial sections were used for immunocytochemical detection of tryptase‐positive mast cells. It was observed that S‐100‐positive cells have the same morphology and localization as the tryptase‐positive mast cells, which indicated that S‐100‐positive cells are most probably mast cells with abilities as dendritic cells. In conclusion, for the first time, the current study gave evidence that mast cells in this organ possess one more function, such as dendritic cells.