胃肠道脂多糖对奶牛健康及生产性能的影响及其防治措施

脂多糖是革兰氏阴性细菌细胞外膜的主要组成成分,奶牛饲粮中精料比例过高或有效中性洗涤纤维含量过低均会显著增加胃肠道脂多糖含量。脂多糖可与pH等胃肠道环境因素共同作用,损伤胃肠道上皮,一旦胃肠道上皮受损,脂多糖便会易位进入机体外周循环系统,导致奶牛机体发生一系列免疫代谢反应,进而影响奶牛健康及生产性能。本文从脂多糖的结构及来源、胃肠道脂多糖对奶牛健康及生产性能的影响及其缓解方法方面进行综述,以期为现代化奶牛生产中保障奶牛健康、提高奶牛生产性能提供理论依据。

Effects of Gastrointestinal Endotoxin on Health and Production Performance of Dairy Cows and Prevention Methods

Endotoxin is a composition of cell outer membrane of Gram negative bacteria, feeding high-concen-trate or low-neutral detergent fibre diets can result in a remarkably increased content of gastrointestinal endotox-in. Gastrointestinal environmental factor such as endotoxin and pH can cooperate to damage epithelial cells, then endotoxin will translocate from the gastrointestinal tract into peripheral circulation which will cause a series of immune metabolic changes, and affect the health and production performance of cows. This article reviewed structure and source of endotoxin, effects of gastrointestinal endotoxin on health and production performance of dairy cows and the prevention methods, in purpose to provide references for ensure health and enhance produc-tion performance of cows.