玉米赤霉烯酮对母猪繁殖性能和胎盘免疫相关基因表达量的影响

本试验旨在研究饲粮中添加玉米赤霉烯酮(ZEN)对母猪繁殖性能和胎盘免疫相关基因表达量的影响。选择胎次相近、体重200 kg、妊娠第30天的长×大二元杂交母猪40头,随机分为2组,每组20个重复,每个重复1头。对照组饲喂基础饲粮,试验组饲粮在基础饲粮中添加1.5 mg/kg的ZEN。试验期74 d。结果表明,与对照组相比:1)饲粮中添加ZEN显著提高了妊娠期母猪死胎数和弱仔猪数(P0.05),显著降低了母猪总产仔数(P0.05);2)饲粮中添加ZEN显著提高了妊娠期母猪血清孕酮含量(P0.05);3)饲粮中添加ZEN显著提高了妊娠期母猪胎盘中Toll样受体-2(TLR-2)和孕酮受体(PGR)基因表达量(P0.05)。由此可见,母猪妊娠期饲粮中添加1.5 mg/kg ZEN可显著降低母猪总产仔数,并显著提高死胎数和弱仔猪数。饲粮中低水平的ZEN对母猪繁殖性能仍产生不利影响。

Effects of Zearalenone on Reproductive Performance and Placenta Immunity Related Gene Expression of Sows

This experiment was to conducted to study the effects of dietary zearalenone ( ZEN) on reproductive performance and placenta immunity related gene expression of sows. Forty 30 days gestation sows with similar parity and 200 kg body weight were randomly divided into 2 groups with 20 replicates per group and 1 pig per replicate. Pigs in the control group were fed a basal diet, while others in the experimental group were fed the basal diet supplemented with 1.5 mg/kg ZEN. The experiment lasted for 74 days. The results showed that com?pared with the control group:1) dietary supplemented with ZEN significantly increased the number of stillborn piglets and number of weak born piglets of pregnant sows ( P<0.05) , and significantly decreased the number of total born piglets of sows ( P<0.05); 2) dietary supplemented with ZEN significantly increased the serum progesterone content of pregnant sows (P<0.05); 3) dietary supplemented with ZEN significantly increased the expressions of Toll?like receptor?2 ( TLR?2) and progesterone receptor ( PGR) in placenta of pregnant sows ( P<0.05) . In conclusion, dietary supplemented with 1.5 mg/kg ZEN can significantly decrease the number of total born piglets, and significantly increase the number of stillborn piglets and number of weak born piglets of pregnant sows. Dietary low level of ZEN still has adverse effect on reproductive performance of sows.