Evaluation of the therapeutic effect of potassium permanganate at early stages of an experimental acute infection of Flavobacterium columnare in channel catfish,Ictalurus punctatus (Rafinesque) |
| |
Authors: | Ahmed M Darwish Andrew J Mitchell David L Straus |
| |
Affiliation: | US Department of Agriculture, Harry K. Dupree‐Stuttgart National Aquaculture Research Center, Agricultural Research Service, Stuttgart, AR, USA |
| |
Abstract: | The efficacy of potassium permanganate (KMnO4) against the early stages of an experimental acute infection of Flavobacterium columnare in channel catfish, Ictalurus punctatus, was evaluated. Fish were experimentally challenged by waterborne exposure for 2 h to F. columnare after cutaneous abrasion, and treated with KMnO4 at 2.0 mg L?1 above the KMnO4 demand at 0, 1, 2 or 4 h postchallenge for 24 h. Challenged non‐treated fish acted as a positive control and non‐challenged non‐treated fish acted as a negative control. Fish challenged and treated with KMnO4 at 0, 1, 2 or 4 h postchallenge had mortalities of 26%, 63%, 64% and 83% respectively. The mortality of challenged fish treated with KMnO4 at 0 h postchallenge (26%) was significantly less than the positive control (77%). The mortalities of challenged fish treated at 1, 2 or 4 h postchallenge were not significantly different from the positive control fish. The results suggest that KMnO4 has a clear therapeutic value in early stages of columnaris infection but limited therapeutic value once the infection has progressed. |
| |
Keywords: | potassium permanganate columnaris Flavobacterium columnare channel catfish Ictalurus puntatus |
|
|