鸡大肠杆菌抗体效价与攻毒保护率的平行关系试验研究

用与制造菌苗株一致的培养物制备检测抗原,检测30日龄雏鸡免疫后抗体效价,对不同抗体滴度的雏鸡进行了攻毒保护性试验.结果表明,抗体效价在3log2以下不具备保护力;抗体效价为4log2攻毒保护率≥60%;抗体效价为5log2时,保护率在80%以上;抗体效价在7log2时,保护率可达100%.

Study of the paralleled relationship between the valence of antibody for chicken E.coli and the protection rate of toxic substances

In the experiment we used the antigen to detect the valence of antibody of 30 days immuned chicken,which is the same antigen with the strains of chicken E.coli inactived vaccine.We carried out conteracting toxic substances experiment utilizing the chicken with different valences of antibody.The result shows when the valence of antibody was less than 3log2,the immuned chicken could not be protected;when the valence of antibody was 4log2,5log2 and 7log2,the protection rates of the immuned chicken were more than 60%,80%and 100%,respectively.