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CAV对BWEL-SPE鸡的致病性试验及毒价测定
引用本文:夏长友,王笑梅,关云涛,陈洪岩,刘怀然,南锡,王秀荣. CAV对BWEL-SPE鸡的致病性试验及毒价测定[J]. 中国预防兽医学报, 2002, 24(1): 10-12
作者姓名:夏长友  王笑梅  关云涛  陈洪岩  刘怀然  南锡  王秀荣
作者单位:1. 中国农业科学院哈尔滨兽医研究所,黑龙江,哈尔滨,150001
2. 农业部动物检疫所
摘    要:本实验用鸡传染性贫血病病毒标准株(CAV和Cux-1)和国内分离株(CAV M9905 CAV和H9906分别对BWEL-SPF雏鸡1-7家系进行1日龄和1月龄攻毒的致病性试验。1日龄雏鸡接种CAV Cux-1毒株,12天后观察到感染鸡的喙、腿、冠和爪等部位颜色变浅,16天剖杀,观察剖检变化,并进行IFA和PCR检测,确定感染率和CAV毒价。结果CAV Cux-1株对1日龄BWEL-SPF雏鸡半数感染量(CID50)为10^4.3/0.2ml。同时检测到CAV Cux-1株对1月龄BWEL-SPF雏鸡发病率为60%;CAVM9905和CAV H9906对1日龄BWEL-SPF雏鸡发病率为100%,死亡率为40%、20%。

关 键 词:CAV BWEL-SPF鸡 致病性 毒价 鸡传染性贫血病毒
文章编号:1008-0589(2002)01-0010-03
修稿时间:2001-02-05

The Titer of CAV and the Pathogenic Test to BWEL-SPF Chicken
XIA Chang_you,WANG Xiao_mei,GUAN Yun_tao,CHEN Hong_yan ,LIU Huai_ran,NAN Xi ,WANG Xiu_rong. The Titer of CAV and the Pathogenic Test to BWEL-SPF Chicken[J]. Chinese Journal of Preventive Veterinary Medicine, 2002, 24(1): 10-12
Authors:XIA Chang_you  WANG Xiao_mei  GUAN Yun_tao  CHEN Hong_yan   LIU Huai_ran  NAN Xi   WANG Xiu_rong
Affiliation:XIA Chang_you,WANG Xiao_mei,GUAN Yun_tao,CHEN Hong_yan *,LIU Huai_ran,NAN Xi **,WANG Xiu_rong
Abstract:To investigate the pathogenicity of CAV_Cux1,CAV M9009 and CAV H9906 which were isolated from china,1_day_old BWEL_SPF chickens are challenged with these viruses.It demonstrates that the CID 50 of CAV_Cux1 to 1_day_old chickens is 10 4.3/0.2ml.And the morbidity of CAV_Cux1,CAV M9905 and CAV H9906 to 1_day_old BWEL_SPF chickens are 100%,40% and 20%respectively.
Keywords:CAV  BWEL_SPF chicken  Pathogenicity  Virus titer
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