Cervid herpesvirus 2 infection in reindeer: A review |
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| Authors: | Carlos G das Neves Swaantje Roth Espen Rimstad Etienne Thiry Morten Tryland |
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| Institution: | 1. Section of Arctic Veterinary Medicine, Department of Food Safety and Infection Biology, The Norwegian School of Veterinary Science, Stakkevollveien 23, NO – 9010 Tromsø, Norway;2. Institut für Virologie, Freie Universität Berlin, 10115 Berlin, Germany;3. Section of Microbiology, Immunology and Parasitology, Section of Food Safety, Department of Food Safety and Infection Biology, The Norwegian School of Veterinary Science, P.O. Box 8146, NO – 0033 Oslo, Norway;4. Virology and Viral Diseases, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liège, 4000 Liège, Belgium |
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| Abstract: | Herpesviruses of the genus Varicellovirus are known to infect and cause disease in a variety of ruminant species, but the impact of cervid herpesvirus 2 (CvHV2) in reindeer (Rangifer tarandus) is mostly unknown. Reindeer is a circum-polar species with a total estimated number of more than 5 million animals. Mortality may reach high values, as in northern Norway, especially in calves (37%; 2005–2006), and disease can potentially account for some of this mortality. CvHV2 has been isolated during a natural outbreak of infectious keratoconjunctivitis, indicating an etiologal link. Serological screening has shown that CvHV2 infection is prevalent in Northern Norway and experimental infection studies have demonstrated that viremia, latency and vertical transmission occur for CvHV2. The present review aims at summarizing current knowledge on the epidemiology, pathogenesis and molecular virology of CvHV2. |
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| Keywords: | Reindeer Cervid herpesvirus 2 Epidemiology Eye disease |
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