Research Progress on Pharmacological Action of Rifaximin and its Application in Prevention and Treatment of Dairy Cow Disease

Rifaximin is a kind of new drug for the treatment of dairy cow disease which antimicrobial spectrum is wide.It has a strong antibacterial activity and unique antibacterial mechanism.Rifaximin is suit for local administration because it is no mutagenic,abnormal toxicity,carcinogenicity and reproduction toxicity and so on.In this paper,the physical and chemical properties,action mechanism,pharmacokinetic,pharmacology and toxicology properties,clinical application were investigated and reviewed,so as to provide a theoretical basis for the application in prevention and treatment of animal diseases,and make veterinary workers have a comprehensive understanding of rifaximin and guide the clinical application.