Advance in receptor type protein tyrosine phosphatase Q |
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| Authors: | HUANG Yong-hong SHI Hui-mian ZHOU Xiao-yan XU Hong LUO Zhi-jun XU Fang-yun |
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| Institution: | 1. Department of Pathophysiology, Medical College of Nanchang University, Nanchang 330006, China;
2. Department of Physiology, Medical College of Nanchang University, Nanchang 330006, China |
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| Abstract: | Receptor type protein tyrosine phosphatase Q (PTPRQ) is an unusual protein tyrosine phosphatase that has intrinsic dephosphorylating activity for various phosphatidylinositiol and phospho-tyrosine substrates, especially the phosphatidylinositol activity. Recent data show that PTPRQ has an important role in various biological processes and is associated with some diseases. In this article, the structure and function of PTPRQ and the relationship between PTPRQ and diseases were briefly summarized. |
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| Keywords: | Protein tyrosine phosphatase receptor type Q Hearing loss Neoplasms Cell proliferation |
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