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Use of fluoxetine to treat stereotypical pacing behavior in a brown bear (Ursus arctos)
Institution:1. Faculty of Environmental Sciences and Natural Resource Management, Norwegian University of Life Sciences, P.O. Box 5003, NO-1432 Ås, Norway;2. Faculty of Technology, Natural Sciences and Maritime Sciences, Department of Natural Sciences and Environmental Health, University of Southeast Norway, P.O. Box 5003, NO-3800 Bø, Norway;3. Faculty of Applied Ecology, Agricultural Sciences and Biotechnology, Inland Norway University of Applied Sciences, Campus Evenstad, NO-2480 Koppang, Norway;4. Senckenberg Biodiversity and Climate Research Centre (BIK-F), DE-60325 Frankfurt (Main), Germany;5. Norwegian Institute for Nature Research, P.O. Box 5685, NO-7485 Trondheim, Norway;6. Faculty of Forest Sciences, Swedish University of Agricultural Sciences, 907 36 Umeå, Sweden;1. Psychology, School of Natural Sciences, University of Stirling, Stirling FK9 4LA, Scotland, United Kingdom;2. Biology, University of Bolton, Deane Road, BL3 5AB, Bolton, United Kingdom;1. Center for Animal Welfare, University of California, Davis, USA;2. Department of Animal Science, University of California, Davis, USA;3. AWARE Institute, Portland Oregon, USA;1. Centre for Wildlife Conservation, University of Cumbria, Penrith, U.K.;2. Central Queensland University, Gladstone, Australia;3. Faculty of Education, Health and Sciences, University of Derby, Derby, U.K.;4. Faculty of Art and Sciences, Department of Environmental and Health Studies, Telemark University College, Bø i Telemark, Norway;1. Oregon Zoo, 4001 SW Canyon Rd., Portland, OR 97221, USA;2. Honolulu Zoo, 151 Kapahulu Avenue, Honolulu, HI 96815, USA;3. St Louis Zoo, One Government Drive, St. Louis, MO 63110, USA;4. Oregon Health & Science University - School of Nursing, 3455 SW US Veterans Hospital Rd. Portland, OR 97239-2941, US
Abstract:A 12-year-old, male, brown bear (Ursus arctos) named Abdi exhibited stereotypical pacing behavior. He was kept as a pet for 10 years by local villagers, then he was rescued and taken to the Karacabey Bear Sanctuary in July 2001. His physical condition was extremely poor. Because he had never lived with other bears, he was terrified and refused to integrate with them. After 6 months he was healthy physically but observations by the keepers indicated that he was pacing all day. He was treated with fluoxetine (0.62 mg/kg orally every 24 hours) for 6 months, and had been observed totally for 18 months. After stereotypy ceased completely, he was transferred to the large naturalistic enclosure and did not show any stereotypical behavior during the subsequent observation period (1 year). He was treated successfully using a combination of fluoxetine, the provisioning of extra space, and the addition of novel stimulation in a naturalistic enclosure. The space and stimulation could be sufficient to mimic the therapeutic effect of the pharmacological therapy in the long term.
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