山东省部分地区兔大肠杆菌病发病特点与药敏试验分析

于2011年1月至2012年7月,自山东省潍坊、临沂、淄博、滨州等部分地区送检114份病死兔病例中,经细菌分离鉴定,共分离到45株大肠杆菌。对上述大肠杆菌发病病例及发病日龄分析发现,1~3月龄发病数量占到64.4%;通过对其他病原的分离鉴定发现,不同病例存在球虫、魏氏梭菌、巴氏杆菌、波氏杆菌、链球菌、兔瘟等混合感染问题,混合感染病例占总病例近50%;对分离菌进行了药敏试验,发现其存在不同程度的耐药情况,其中对复方新诺明耐药性高达95.6%,对环丙沙星、阿莫西林、庆大霉素、新霉素的耐药性比率超过60%,而且二重耐药、多重耐药的情况较为普遍。

Characteristics and Antimicrobial Susceptibility of the Isolated Escherichia Coli from Rabbits in Shandong

45 strains of Escherichia coli were isolated from 114 dead rabbits in Shandong province from 2011 January to 2012 July,and 64.4% of incidence was distributed in 1-3 monthes old ages.Mixed infection was popular,and its percentage was high to be 50% in Coccidia,Clostridium perfringens,Pasteurella multocida,Bordetella,Streptococcus,and rabbit plague with Escherichia coli in rabbits.Antimicrobial susceptibility tests show that 95.6% of isolated Escherichia coli srains have resistance to Cotrimoxazole,and more than 60% to Ciprofloxacin,amoxicillin,gentamicin,and neomycin.Some isolated Escherichia coli strains were not sensitive to more than 1 or 2 kinds of antibiotic.