|
|||||
|
|
Lysergic acid diethylamide: sensitive neuronal units in the midbrain raphe |
|
| Authors: | G K Aghajanian W E Foote M H Sheard |
| Abstract: | Units in areas of the midbrain rich in neurons containing serotonin respond to parenteral injections of d-lysergic acid diethylamide by a reversible cessation of spontaneous activity. The dose required is at or below threshold for gross behavioral effects. An inhibition of neurons containing serotonin after administration of d-lysergic acid diethylamide could account for the decreased metabolism of serotonin produced by this drug. |
| Keywords: | |