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Antioxidant Effects of Oats Avenanthramides on Human Serum |
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| Authors: | LIU Sen YANG Nan HOU Zhao-hua YAO Yang L Li ZHOU Xian-rong REN Gui-xing |
| Institution: | 1. Institute of Comprehensive Utilization of Agricultural Products, Shanxi Academy of Agriculture Sciences, Taiyuan 030031, P.R. China 2. Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, P.R. China 3. The General Hospital of Chinese People 's Armed Police Forces, Beijing 100039, P.R. China |
| Abstract: | The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study.Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon.Plasma lipid peroxides and antioxidant status were measured.For 8 capsules (containing 3.12 mg avenanthramides)groups,the levels of serum superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantly increased by 8.4 and 17.9％,respectively (P＜0.05),and malondialdehyde (MDA) level significantly decreased by 28.1％.The total cholesterol (TC),triglyceride (TG),and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1,28.1,and 15.1％,respectively (P＜0.05).The high density blood lipoprotein cholesterol (HDL-C) levels in the same treat was increased by 13.2％.Based on our research,it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans.It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy. |
| Keywords: | oats avenanthramides human serum antioxidation SOD MDA LDL-C HDL-C |
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