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Extraction Procedure,Characteristics, and Feasibility of Caulerpa microphysa (Chlorophyta) Polysaccharide Extract as a Cosmetic Ingredient
Authors:Meng-Chou Lee  Han-Yang Yeh  Wen-Ling Shih
Institution:1.Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan; (M.-C.L.); (H.-Y.Y.);2.Center of Excellence for Ocean Engineering, National Taiwan Ocean University, Keelung City 20224, Taiwan;3.Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung City 20224, Taiwan;4.Department of Biological Science and Technology, National Pingtung University of Science and Technology, 1, Shuefu Rd., Pingtung 91201, Taiwan
Abstract:The green alga Caulerpa microphysa, which is native to Taiwan, has a relatively high economic value and a well-developed culture technique, and is used mainly as a foodstuff. Its extract has been shown to exhibit antitumor properties, but the polysaccharide content of the extract and its anti-inflammatory and wound-healing effects and moisture-absorption and -retention capacity remain unknown. Hence, the objective of this study was to evaluate the potential of the polysaccharides in C. microphysa extract (CME) for use in cosmetics. The overall polysaccharide yield from the CME was 73.93% w/w, with four molecular weight fractions. The polysaccharides comprised 59.36 mol% mannose, 27.16 mol% glucose, and 13.48 mol% galactose. In addition, the CME exhibited strong antiallergic, wound-healing, transdermal-delivery, and moisture-absorption and -retention effects. In conclusion, the results suggested that CME potentially has anti-inflammatory and wound-healing effects and a good moisture capacity, which can be used in cosmetic applications.
Keywords:Caulerpa  polysaccharides  anti-inflammation  moisture capacity  wound healing
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