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猪13号染色体上脂肪沉积相关QTL定位与候选基因研究进展
引用本文:何小平,彭中镇,刘榜.猪13号染色体上脂肪沉积相关QTL定位与候选基因研究进展[J].中国畜牧兽医,2007,34(12):34-38.
作者姓名:何小平  彭中镇  刘榜
作者单位:华中农业大学动物科技学院动物分子生物学与育种实验室,华中农业大学农业动物遗传育种与繁殖教育部重点实验室,武汉 430070
摘    要:目前已有多个影响脂肪沉积的QTL定位于猪13号染色体上。作者综述了猪13号染色体脂肪沉积相关QTL的定位情况,并对该染色体上影响脂肪沉积的基因进行了介绍,以希望通过比较基因组学和位置候选克隆的方法,寻找猪脂肪沉积相关的候选基因,进而进行连锁分析或关联研究,找到适合在育种实践中进行应用的标记。

关 键 词:  13号染色体  脂肪沉积  数量性状基因座  候选基因  
文章编号:1671-7236(2007)12-0034-05
收稿时间:2007-07-06
修稿时间:2007年7月6日

Advance in the Research of Quantitative Trait Loci and Candidate Genes Correlated with Fat Deposition on Porcine Chromosome 13
HE Xiao-ping,PENG Zhong-zhen,LIU Bang.Advance in the Research of Quantitative Trait Loci and Candidate Genes Correlated with Fat Deposition on Porcine Chromosome 13[J].China Animal Husbandry & Veterinary Medicine,2007,34(12):34-38.
Authors:HE Xiao-ping  PENG Zhong-zhen  LIU Bang
Institution:Lab of Molocular Biology and Animal Breeding,Key Laboratory of Agricultural Animal Genetics,Breeding and Reproduction of Ministry of Education,Huazhong Agricultural Univeristy,Wuhan 430070,China
Abstract:Fat deposition is always the key point of research. Many quantitative trait loci have been mapped on porcine chromosome 13 at present. In this paper, we introduced quantitative trait loci and candidate genes correlated with fat deposition on this chromosome. We can quest for candidate genes for fat deposition by comparative genomics and positional candidate clone approach in future, and then do linkage analysis or association analysis to check the effects of candidate genes, and apply the study results to animal breeding at last.
Keywords:pig  chromosome 13  fat deposition  quantitative trait locus  candidate gene
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