| 脂质体制备方法的研究进展 |
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| 引用本文： | 王瑞莲,刘成梅,刘伟. 脂质体制备方法的研究进展[J]. 农产品加工．学刊, 2007, 0(8): 12-14 |
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| 作者姓名： | 王瑞莲 刘成梅 刘伟 |
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| 作者单位： | 南昌大学,食品科学教育部重点实验室,江西,南昌,330047;南昌大学,中德食品工程中心,江西,南昌,330047 |
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| 基金项目： | 教育部长江学者和创新团队发展计划创新团队项目 |
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| 摘 要： | 脂质体是磷脂自聚集而形成的双分子层结构,作为一种重要载体,具有保护药物、提高药效、减少制剂对机体的毒性和提高药物的靶向性等方面的优越性。概述了薄膜蒸发法、高压乳匀法、逆向蒸发法、乙醇注入法及改良乙醇注入法、微乳冷却法、冻融法和冷冻干燥法等几种脂质体的制备方法,以及脂质体的评价指标。
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| 关 键 词： | 脂质体 制备方法 评价指标 |
| 文章编号： | 1671-9646（2007）08-0012-03 |
| 修稿时间： | 2007-06-05 |
Research Progress on Preparation Methods of Liposome |
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| Wang Ruilian,Liu Chengmei,Liu Wei. Research Progress on Preparation Methods of Liposome[J]. Nongchanpin Jlagong.Xuekan, 2007, 0(8): 12-14 |
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| Authors: | Wang Ruilian Liu Chengmei Liu Wei |
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| Affiliation: | 1.The Key Laboratory of Food Science of MOE,Nanchang University,Nanchang,Jiangxi 330047,China; 2.Sino-German Food Engineering Center,Nanchang University,Nanchang,Jiangxi 330047,China |
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| Abstract: | Liposome be made from phospholipid self-aggregation,as an important drugs carrier,it has many advantages,such as protecting drugs,increasing drugs effect,minimizing toxicity of drugs,increasing drugs targeting and so on.The evaluation guideline and the preparation methods of liposome such as thin film evaporation method,high-pressure homogenizer method,reverse phase evaporation vesicle method,ethanol injection-extrude and modified ethanol injection-extrude method,microemulsion cooling method,freeze-thawing method and lyophilization method are reviewed in this paper. |
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| Keywords: | liposome preparation methods evaluation guideline |
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