不同免疫途径对商品蛋雏鸡新城疫黏膜及血清抗体的影响

通过不同的免疫途径对商品蛋雏鸡进行免疫,探讨不同的免疫途径对商品蛋雏鸡新城疫(Newcastle disease,ND)黏膜抗体及血清抗体的影响。结果表明,同时用新城疫弱毒疫苗免疫后,不同的免疫途径产生的新城疫黏膜抗体及血清抗体效价有较大差异。采用喷雾法于3日龄首免,15日龄二免,25日龄三免,鸡体产生保护水平(6 log2)以上的ND黏膜抗体和血清抗体最快、抗体水平最高、维持时间最长、总体免疫效果最好,而采用饮水免疫的试验组产生的ND黏膜抗体和血清抗体水平均不高,总体免疫效果最差。

Effect of Immune Mucosal Antibody and Serum Antibody of Newcastle Disease Used Different Immunization Approachs for Layer Chicken

In order to explore the effects of immune mucosal antibody and serum antibody of Newcastle disease used different immunization approachs for layer chicken, we used different immunization approachs immunized the commercial layer chickens.The results showed that the Newcastle mucosal antibody and serum antibody titers of chickens were significantly different after they were immunized with Newcastle disease attenuated vaccine by different immune pathways at the same time. Three times of immunization by spraying when 3-day-old, 15-day-old and 25-day-old, respectively, chicken produced ND mucosal antibody and serum antibody above the protective level （6 log2） most fastly, the highest level of antibody maintained the longest time, the overall immune effect was the best.While the levels of ND mucosal antibody and serum antibody of chickens immunized by drinking water were not high, and the overall immune effect was the worst.