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| 长爪沙鼠脑底动脉Willis环变异缺失类型与脑缺血模型症状相关性分析 | |
| 引用本文： | 郑振峰,杜小燕,王迎,路静,高丰,陈振文.长爪沙鼠脑底动脉Willis环变异缺失类型与脑缺血模型症状相关性分析[J].中国兽医学报,2011,31(6). |
| 作者姓名： | 郑振峰 杜小燕 王迎 路静 高丰 陈振文 |
| 作者单位： | 1. 吉林大学,畜牧兽医学院,吉林长春130062;首都医科大学,基础医学院,北京100086 2. 首都医科大学,基础医学院,北京100086 3. 吉林大学,畜牧兽医学院,吉林长春130062 |
| 基金项目： | 国家自然科学基金资助项目(30570261,31071988); 国家科技支撑计划资助项目(2009BAI83B02) |
| 摘 要： | 通过观察398只长爪沙鼠右侧颈总动脉结扎脑缺血模型,比较研究其脑底动脉Willis环缺失类型和半脑缺血模型症状的相关性。结果显示,长爪沙鼠脑底动脉Willis环的前、后交通支各有4种类型。在Willis环后交通支缺失的前提下,当行单侧颈总动脉结扎时,一侧脑缺血症状显著程度与前交通支变异类型有关,其中前交通支完整型与其余3种类型的症状有显著性差异(P=0.000)。结果表明,经颈总动脉结扎后半脑缺血模型高发生率和典型症状的基础是Willis环后交通支缺失并伴有前交缺失或细小为前提的。 |
| 关 键 词： | 长爪沙鼠 Willis环 脑缺血模型 |
Analysis of the relationship between the variation of Willis circle and the symptoms of ischemic model in gerbils |
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| ZHENG Zhen-feng,DU Xiao-yan,WANG Ying,LU Jing,GAO Feng,CHEN Zhen-wen.Analysis of the relationship between the variation of Willis circle and the symptoms of ischemic model in gerbils[J].Chinese Journal of Veterinary Science,2011,31(6). | |
| Authors: | ZHENG Zhen-feng DU Xiao-yan WANG Ying LU Jing GAO Feng CHEN Zhen-wen |
| Institution: | ZHENG Zhen-feng1,2,DU Xiao-yan2,WANG Ying2,LU Jing2,GAO Feng1,CHEN Zhen-wen2(1.College of Animal Science and Veterinary Medicine,Jilin University,Changchun 130062,China,2.Department of Laboratory Anima Science,Capital Medical University,Beijing 100086,China) |
| Abstract: | In the present study,we used 398 gerbils to investigate post-UCO(Unilateral carotid occlusion) ischemic symptoms and possible correlations of anterior communicating arteries(ACoA) and posterior communicating arteries(PCoA) patterns.The results show that there are the respectivel four types of the ACoAs and PCoAs in the CoW.The severity of the neurological symptoms after UCO was significantly related to the patterns of the ACoAs when PCoAs were absent.The proportion of UCO ischemia in gerbils with incomplete... |
| Keywords: | mongolian gerbil circle of Willis ischemic model |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |