Influence of pneumoperitoneum and postural change on the cardiovascular and
respiratory systems in dogs |
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Authors: | Young Tae PARK Shozo OKANO |
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Institution: | 1)Laboratory of Small Animal Surgery, Kitasato University, 35–1, Higashi 23-bancho, Towada, Aomori 034–8628, Japan |
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Abstract: | We investigated the influence of pneumoperitoneum#(PP) and postural change under
inhalation anesthesia with isoflurane, which is routinely used in dogs, on the
cardiovascular and respiratory systems. As test animals, 6 adult beagles were used. To
induce anesthesia, atropine, butorphanol and propofol were intravenously injected.
Anesthesia was maintained with 1.3 MAC (1.7%) isoflurane. The following were the
experiment conditions: I:E ratio, 1:1.9; tidal air exchange, 20 ml/kg;
and ventilation frequency, 14 times/min. Respiration was regulated so that the
PaCO2 was approximately 35 to 40 mmHg before the start of the experiment. PP
with CO2 (intraperitoneal pressure 15 mmHg) and a postural change (15°C) was
performed during the experiment. As parameters of circulatory kinetics, heart rate (HR),
mean aortic pressure (MAP), mean pulmonary arterial pressure (MPAP), central venous
pressure (CVP), femoral venous pressure (FVP) and cardiac output (CO) were measured. As
parameters of respiratory kinetics, airway pressure (PAW) and blood gas (BG) were
measured. There were significant increases in HR, MAP, MPAP, CVP, FVP, CO, PAW and
PaCO2 after PP in the horizontal position. There were significant increases
in CVP, FVP, PAW and PaCO2 after PP in the Trendelenburg position. There were
significant increases in the MPAP, CVP, FVP, PAW and PaCO2 after PP in the
inverse Trendelenburg position. There was a significant difference in FVP after PP between
the Trendelenburg position and inverse Trendelenburg position. The results of this
experiment suggest that appropriate anesthesia control, such as changing the ventilation
conditions after PP, is required for laparoscopic surgery under inhalation anesthesia with
isoflurane. |
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Keywords: | cardiovascular system laparoscopic surgery pneumoperitoneum postural change respiratory system |
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