氟罗沙星对鸡败血支原体和大肠杆菌混合感染的疗效

以人工诱发鸡败血霉形体和大肠杆菌混合感染模型，评价氟罗沙星的疗效。按每升水加入２５ｍｇ、５０ｍｇ及１００ｍｇ氟罗沙星及５０ｍｇ环丙沙星的用量给病鸡饮水给药，连续５天，对混合感染鸡的治愈率分别是８６．７％、９０．０％、９０．０％及８３．３％，而感染对照组的死亡率为６３．３％；用药组的相对增重率分别为１０１．３％、１０５．７％、１０７．２％及１０２．４％，均显著高于感染对照组（５８５．５％，Ｐ〈０．０１）

Efficacy of Fleroxacin in the Control of Infection with Mycoplasma galliseptican and E.coli in Chickens

The disease model was infected in 180 chickens byinoculating Mycoplasma gallisepticam into the trachea and E.coli into the breastmuscle.All the therapeutic groups of chickens were medicated for 5 successive days viadrinking water with fleroxacin (25,50,100mg/L) and ciprofloxacin(50mg/L),respectively,theother group was unmedicated as infected control.The curative rates of the diseased groupstreated with 25,50,100mg/L of fleroxacin and 50 mg/L of infected control group was63.3%.Percentage of relative body weight gain of the diseased groups treated with25,50,100mg/L of fleroxacin and 50mg/L of ciprofloxacin were 101.3%,105.7%,107.2% and102.4%,respectively.Percentage of relative body weight gain of infected control group was58.5%,and it was lower than that of treated groups (P〈0.01)