Combination fibrinolytic therapy in the treatment of chronic septic pleuropneumonia in a Thoroughbred gelding |
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Authors: | DI Rendle Sk Armstrong Kj Hughes |
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Affiliation: | School of Animal and Veterinary Sciences, Charles Sturt University, Locked Bag 588, Wagga Wagga, New South Wales, Australia. daverendle@btinternet.com. |
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Abstract: | This report documents the treatment of a case of chronic pleuropneumonia in a 3-year-old Thoroughbred gelding. A recombinant tissue plasminogen activator (tenecteplase) and a recombinant deoxyribonucleic acidase (alphadornase) were infused into the pleural cavity as adjunctive therapy in the early stages of treatment. Instillation of fibrinolytic drugs was associated with a subjective reduction in the amount of fibrin deposition and decreased fluid accumulation within the pleural cavities. Fibrinolytic therapy may be a useful adjunctive therapy in selected cases of intrapleural disease in horses. |
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Keywords: | deoxyribonuclease fibrinolysis parapneumonic effusion pleuropneumonia Salmonella tissue plasminogen activator |
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