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美洲大蠊对低免疫力小鼠免疫功能的影响
引用本文:周琼,吴珍泉,李忠荣,刘景,王长康. 美洲大蠊对低免疫力小鼠免疫功能的影响[J]. 福建农林大学学报(自然科学版), 2008, 37(5)
作者姓名:周琼  吴珍泉  李忠荣  刘景  王长康
作者单位:1. 福建省农业科学院中心实验室,福建,福州,350003;福建农林大学教育部生物农药与化学生物学重点实验室,福建,福州,350002
2. 福建农林大学教育部生物农药与化学生物学重点实验室,福建,福州,350002
3. 福建省农业科学院畜牧兽医研究所,福建,福州,350013
4. 福建农林大学动物科学学院,福建,福州,350002
基金项目:福建省科技厅科技计划 
摘    要:用环磷酰胺造低免疫力小鼠模型,再分别用低、中、高剂量的美洲大蠊粉给小鼠灌胃,研究虫粉对小鼠吞噬细胞的吞噬指数、血清溶血素含量、外周血CD4/CD8和免疫器官指数的影响,结果表明,高剂量虫粉组的血清溶血素含量和外周血CD4/CD8与模型对照组相比均有显著提高(P<0.05),中、高剂量虫粉组吞噬细胞的吞噬指数比模型对照组显著提高(P<0.05),说明美洲大蠊虫粉能提高低免疫力小鼠的免疫功能.

关 键 词:美洲大蠊  免疫功能  吞噬指数  血清溶血素  外周血CD4/CD8

Effect of Periplaneta americana L.on immune function of mice with low immunity
ZHOU Qiong,WU Zhen-quan,LI Zhong-rong,LIU Jing,WANG Chang-kang. Effect of Periplaneta americana L.on immune function of mice with low immunity[J]. Journal of Fujian Agricultural and Forestry University, 2008, 37(5)
Authors:ZHOU Qiong  WU Zhen-quan  LI Zhong-rong  LIU Jing  WANG Chang-kang
Abstract:Cyclophosphamide was used to set up the low immunity mice model,then low,middle and high dosages of Periplaneta americana L.meal were filled to the mice.Carbon clearance index,the content of serum hemolysin,CD4/CD8 ratio of peripheral blood and immune organ index of mice were studied.The results showed that the content of serum hemolysin,CD4/CD8 ratio of peripheral blood of the high dosage treatment were significantly higher than those of model control.Carbon clearance indexes of middle and high dosage treatments were significantly higher than that of model control.It suggested that Periplaneta americana L.could increase immune function of low immunity mice.
Keywords:Periplaneta americana L.  immune function  carbon clearance index  serum hemolysin  CD4/CD8 ratio of peripheral blood
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