| 兔脑炎微孢子虫感染对家兔细胞免疫功能的影响 |
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| 引用本文： | 段艳,潘耀谦,张柳平.兔脑炎微孢子虫感染对家兔细胞免疫功能的影响[J].内蒙古农业大学学报(自然科学版),2003,24(3):109-111. |
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| 作者姓名： | 段艳 潘耀谦 张柳平 |
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| 作者单位： | 军需大学军事兽医系基础兽医学教研室,长春,130062 |
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| 摘 要： | 以临床症状和病理学变化确诊为兔脑炎微孢子虫感染的家兔为研究对象,用流式细胞计数仪检测外周血CD4+、CEB+细胞比例,并与健康家兔进行比较。结果表明兔脑炎微孢子虫病患兔外周血CD4+细胞比例与对照组相比无明显变化,P>0.05;而CD8+细胞比例明显高于对照组,CD4+/CD8+比值则明显低于对照组,P<0.05。提示兔脑炎微孢子虫患兔外周血CD4+/CD8+比值明显下降,机体免疫力减弱,可能是导致兔脑炎微孢子虫入侵机体,引起家兔发病的重要原因。
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| 关 键 词： | 兔脑炎 微孢子虫 家兔 细胞 免疫功能 影响因素 临床症状 病理学变化 流式细胞计数仪 |
| 文章编号： | 1009-3575(2003)03-0109-03 |
| 修稿时间： | 2003年2月17日 |
EFFECT OF ENCEPGALITOZOON CUNICULI ON CELLULAR LMMUNITY OF RABBIT |
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| DUAN Yah,PAN Yao-qian,ZHANG Liu-ping.EFFECT OF ENCEPGALITOZOON CUNICULI ON CELLULAR LMMUNITY OF RABBIT[J].Journal of Inner Mongolia Agricultural University(Natural Science Edition),2003,24(3):109-111. |
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| Authors: | DUAN Yah PAN Yao-qian ZHANG Liu-ping |
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| Abstract: | Diagnosised by clinical symptoms and pathologic variation, CD4+, CD8+ lymphocyte phenotype were detected by FCM in rabbit infected with Encephalitozoon cuniculi, and compared with health rabbit. The results showed that the CD8+ cells was important and the ratio of CD4+/CD8+ could reflect the balance of T lymphocyto in vivo. The obvious descendence of the ratio of CD4+/CD8+ caused the descent of the rabbit immunity. Then the rabbit infected with Encephalitozoon cuniculi. |
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| Keywords: | Encephalitozoon cuniculi cellular immunity CD4+cell CD8 + cell |
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