A heteroploid permanent cell line originating from embryonic calf thyroid supporting the replication of all known bovine adenovirus serotypes |
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| Authors: | M Benk? A Bartha K M?stl F Bürki |
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| Institution: | Veterinary Medical Research Institute of the Hungarian Academy of Sciences, Budapest. |
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| Abstract: | An embryonic calf thyroid cell culture was established as a permanent heteroploid cell line, which is now in its 150th subculture. It allowed replication of all nine bovine adenovirus serotypes at its 15th as well as its 60-150th passages. All viruses induced typical cytopathic effects. Yields obtained on the permanent calf thyroid line were, on average, 0.8 log10 lower than those obtained on primary calf testicle cells. |
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