Immunohistochemistry Diagnosis of an Ovarian Dysgerminoma in One Bitch |
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| Authors: | JK Park MJ Goo IH Hong MR Ki JY Han KS Jeong |
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| Institution: | Department of Veterinary Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu, Korea |
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| Abstract: | An ovarian enlargement (diameter, 8 cm) was identified and surgically excised from a 5-year-old female dog. Microscopic examination of the multinodular neoplasm revealed sheets of polygonal neoplastic cells with large nuclei, frequent mitosis, necrosis and haemorrhage. Immunohistochemically, the neoplastic cells were positive for vimentin and alkaline phosphatase but were negative for CD3, CD79a, cytokeratin, alpha-fetoprotein, inhibin-α and S-100. The histopathological diagnosis of the mass was unilateral ovarian dysgerminoma. |
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