健康人群乙型肝炎病毒感染血清标志模式及免疫状况的分析

目的:了解健康人群HBV感染及获得性免疫的状况,为更好的防治乙型肝炎提供客观依据.方法:采用ELISA法检测健康体检人群血清中HBsAg、HBsAb、HBeAg、HBeAb、HBcAb五项指标并对结果进行统计学分析.结果:8995例健康人群血清中HBV抗原抗体系统五项指标阴性者为48.4%,抗-HBs阳性者为44.7%,感染指标阳性者为6.9%,出现10种感染模式:五项指标均阴性;抗-HBs阳性;HBsAg阳性;抗-HBe阳性;HBsAg、HBeAg、HBcAb三项阳性;HBsAg、HBeAb、HBcAb三项阳性;HBsAg、HBeAb两项阳性;HBsAb、HBeAb、HBcAb三项阳性;HBeAb、HBcAb两项阳性和HBsAg、HBcAb两项阳性.结论:健康人群HBV感染近年来明显下降而免疫力明显上升,但尚有近1/2的人缺乏免疫力,并存在少数传染性强的乙型肝炎患者;应提倡健康人群普种乙肝疫苗,即使注射了乙肝疫苗也要注意自身一般性预防,常规检测乙肝五项指标,及时发现病情及早治疗.

The Analysis on the Infection Sera Marker Modes of Hepatitis B Virus and Immune State of the Health Crowd

Objective:To provide the objective basis for prevention and treatment for the HBV infects,the infection sera modes of HBVA and the acquired immunity state of the health crowd were investigated.Method:Five indices HBsAg,HBsAb,HBeAg,HBeAb,HBcAb were detected and statistically analyzed by the ELISA method.Result: negative persons of Five indices of HBV antigen antibody system in 8995 health crowd sera were 48.4%,positive persons of HBsAb were 44.7%,infection positive indices were 6.9% and appeared 10 kinds infection modes,namely: Five indices were all negative;HBsAb was positive;HBsAg was positive;HBeAb was positive;(5) three indices of the HBsAg,HBeAg,HBcAb were positive;three indices of the HBsAg,HBeAb,HBcAb were positive;two indices of the HBsAg,HBeAb were positive;three indices of the HBsAb,HBeAb,HBcAb were positive;two indices of the HBeAb,HBcAb were positive;two indices of the HBsAg,HBcAb were positive.Conclusion:The health crowd infected with HBV obviously drops and the immunity obviously rises in recent years,but still nearly 1/2 of the persons lack the immunity,there are a few strong infective hepatitis B patients.It's recommended that the healthy crowd receive hepatitis B vaccine.Even those who have injected hepatitis B vaccine give attention to prevention and the routine measures five indices of hepatitis B so that the abnormal can have early treatment.