Systemic lupus erythematosus in a cat: fulfillment of the American Rheumatism Association criteria with supportive skin histopathology |
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Authors: | CARLO VITALE PETER IHRKE THELMA LEE GROSS & LINDA WERNER |
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Institution: | Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA,;California Dermatopathology Services, Consolidated Veterinary Diagnostics, West Sacramento, CA 95605, USA,;Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA |
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Abstract: | Systemic lupus erythematosus (SLE) was diagnosed in a 9-year-old castrated male Persian cat. The cat described is the first to fulfil four of 11 American Rheumatism Association criteria for the diagnosis of SLE in humans (symmetrical facial dermatitis, thrombocytopenia, positive antinuclear antibodies, oral ulceration) with supportive skin histopathology. Haematological abnormalities included a mild anaemia and severe thrombocytopenia. Skin disease consisted of symmetrical multifocal alopecia with crusting, predominantly on the face. Histopathology of the skin revealed interface dermatitis and interface folliculitis with follicular atrophy. Complete remission was obtained with corticosteroid therapy. |
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Keywords: | alopecia anaemia cats lupus erythematosus thrombocytopenia |
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