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Longitudinal studies of cardiac troponin I concentrations in serum from male cynomolgus monkeys: resting values and effects of oral and intravenous dosing on biologic variability
Authors:Albert Eric Schultze  Jason M. Anderson  Tom G. Kern  Ryan W. Justus  Hsiu‐Yung Cindy Lee  Lynn R. Zieske  Robert James Goodson  Sara Hudson Florey
Affiliation:1. Department of Pathology, Lilly Research Laboratories, A Division of Eli Lilly and Company, Indianapolis, IN, USA;2. Covance Laboratories, Inc., Greenfield, IN, USA;3. Department of Statistics, Lilly Research Laboratories, A Division of Eli Lilly and Company, Indianapolis, IN, USA;4. Singulex, Inc., Alameda, CA, USA
Abstract:
Keywords:Cardiac biomarker  cardiac injury  data interpretation  monkey husbandry  nonhuman primate  safety assessment
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