| 组蛋白修饰与基因调控研究进展 |
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| 引用本文： | 阚盛,翟晓巧. 组蛋白修饰与基因调控研究进展[J]. 河南林业科技, 2009, 29(1): 36-38 |
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| 作者姓名： | 阚盛 翟晓巧 |
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| 作者单位： | 河南农业大学,郑州,450002;河南农业大学,郑州,450002;河南省林业科学研究院,郑州,450008 |
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| 基金项目： | 国家自然科学基金，河南省杰出青年科学基金 |
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| 摘 要： | 组蛋白是染色体基本结构—核小体中的重要组成部分,其N-末端氨基酸残基可发生乙酰化、甲基化、磷酸化、泛素化等多种共价修饰。组蛋白修饰对基因表达的调控有类似DNA遗传密码的调控作用。组蛋白修饰的相关研究,对认识相关基因的功能、进一步了解基因的调控机制具有重要意义。
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| 关 键 词： | 组蛋白修饰 基因调控 |
The Research Progress of Histone modification and Gene regulation |
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| KAN Sheng,ZHAI Xiao-qiao. The Research Progress of Histone modification and Gene regulation[J]. Journal of Henan Forestry Science and Technology, 2009, 29(1): 36-38 |
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| Authors: | KAN Sheng ZHAI Xiao-qiao |
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| Affiliation: | 1.Henan Agricultural University;zhengzhou 450002;China;2.Henan Academy of forestry;Zhengzhou 450008;China |
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| Abstract: | Nucleosome constitutes chromation is a basic unit in eukaryote.Its N-terminal amino acid residues can occur acetylation,methylation,phosphorylation,ubiquitination and other covalent modification.Histone modification on the regulation of gene expression similar DNA genetic code of regulation.Histone modification of the study on the awareness of the relevant gene function,and further understanding of gene regulation mechanism is of great significance. |
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| Keywords: | Histone modification Gene regulation |
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