Co-occurrence of papillomas related to Equus caballus papillomavirus type 2 and cutaneous habronemiasis |
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Authors: | G Vichi I Porcellato L Mechelli G Fantauzzo E Razzuoli P Modesto S Mecocci C Brachelente |
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Institution: | 1. BiEsseA Veterinary Laboratory, Milano, Italy;2. Department of Veterinary Medicine, Perugia, Italy;3. Private Practitioner, Casteltermini, Italy;4. National Reference Center of Veterinary and Comparative Oncology (CEROVEC), Genoa, Italy |
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Abstract: | The present report describes a case of cutaneous papillomatosis related to equine papillomavirus type 2 (EcPV2) with concomitant cutaneous habronemiasis. A 2-year-old female Pura Raza Española horse was referred for a dermatological evaluation because of the onset of cutaneous multifocal, nodular lesions on the face characterised by a warty and partially ulcerated overlying epidermis. Multiple biopsies were taken from these lesions, and cutaneous viral papillomas with a concomitant severe focal eosinophilic dermatitis with intralesional Habronematidae nematode larvae were diagnosed. Immunohistochemistry revealed papillomaviral capsid protein L1 in the epidermal proliferative lesion, confirming the presence of a productive infection. Rt-qPCR confirmed the presence of EcPV type 2. To the authors’ knowledge, this is the first report of EcPV2-related papillomas with concurrent habronemiasis. |
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Keywords: | horse habronemiasis immunohistochemistry papilloma skin |
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