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The effects of IgG2 and of antigen concentration on prozoning in the complement fixation test for bovine brucellosis. |
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| Authors: | D J McNaught R J Chappel G S Allan J A Bourke B A Rogerson |
| Abstract: | Addition of Brucella-specific IgG2 to solutions of Brucella-specific IgG1 initially induced prozoning and at higher concentrations prevented all reaction in the complement fixation test (CFT) for bovine brucellosis. Some infected cattle may be diagnosed as brucellosis-free due to a high ratio of specific IgG2 to IgG1. Increasing the concentration of antigen in the CFT reduced the tendency to prozone. |
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