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| 高剂量辐照鸡胸肉安全性毒理学评价 | |
| 引用本文： | 朱佳廷,冯敏,高美须,严建民,刘春泉,哈益明,杨萍,王德宁.高剂量辐照鸡胸肉安全性毒理学评价[J].核农学报,2011,25(6):1191-1199. |
| 作者姓名： | 朱佳廷 冯敏 高美须 严建民 刘春泉 哈益明 杨萍 王德宁 |
| 作者单位： | 1. 江苏省农业科学院原子能农业利用研究所,江苏南京,210014 2. 中国农业科学院农产品加工研究所,北京,100193 3. 江苏省农业科学院农产品加工所,江苏南京,210014 |
| 基金项目： | 农业部公益性行业科研专项，江苏省农业科技自主创新资金项目 |
| 摘 要： | 以10、15和25kGy剂量辐照处理鸡胸肉,通过动物急性毒性试验、Ames试验、骨髓细胞微核试验、精子畸形试验和30d喂养试验,对其食用安全性进行评价。结果表明,雌、雄小鼠急性经口LD50均大于10g/kg.BW,属实际无毒级;Ames试验、小鼠骨髓微核试验、精子畸形试验结果均为阴性;大鼠30d喂养试验各项指标均未见异... |
| 关 键 词： | 宠物食品 辐照灭菌 安全性 毒理学评价 |
| 收稿时间： | 2011-02-21 |
| 修稿时间： | 2011-06-01 |
SAFETY AND TOXICOLOGY ASSESSMENT OF CHICKEN BREAST FOR HIGH-DOSE IRRADIATION |
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| ZHU Jia-ting,FENG Min,GAO Mei-xu,YAN Jian-min,LIU Chun-quan,HA Yi-ming,YANG Ping,WANG De-ning.SAFETY AND TOXICOLOGY ASSESSMENT OF CHICKEN BREAST FOR HIGH-DOSE IRRADIATION[J].Acta Agriculturae Nucleatae Sinica,2011,25(6):1191-1199. | |
| Authors: | ZHU Jia-ting FENG Min GAO Mei-xu YAN Jian-min LIU Chun-quan HA Yi-ming YANG Ping WANG De-ning |
| Institution: | 1. Institute for Application of Atomic Energy, Jiangsu Academy of Agricultural Sciences, Nanjing, Jiangsu 210014; 2. Institute of Agro-Products Processing Science &;Technology,Chinese Academy of Agricultural Sciences,Beijing 100193; 3. Institute of Agro-Products Processing Science &;Technology,Jiangsu Academy of Agricultural Sciences,Nanjing, Jiangsu 210014 |
| Abstract: | Feeding wholesomeness tests of irradiated chicken breast were studied by using acute oral toxicology, Ames, micronucleus of born marrow cell, spenm shape abnormality in mice and 30d feeding test. The LD50 of all the rats and mice were more than 10g/kg·BW, which means that the pet foods belonged to actually non-toxic grade; ames test, and the tests of micronucleus of born marrow cell, spenm shape abnormality in mice were all negative results; 30d feeding test in rats demonstrated that it had no distinctive effects on routine blood, body weight and biochemical index. It is concluded that pet foods irradiated up to 25 kGy high dose were no safety and toxicology problems. |
| Keywords: | pet foods irradiation sterilization safety toxicology assessment |
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