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巫山神茶对SD大鼠胃损伤的预防效果
引用本文:牟歆,赵欣,李贵节,张雪. 巫山神茶对SD大鼠胃损伤的预防效果[J]. 仲恺农业工程学院学报, 2014, 27(2): 57-59
作者姓名:牟歆  赵欣  李贵节  张雪
作者单位:1重庆第二师范学院生物与化学工程系
摘    要:以巫山神茶为研究对象,就其对盐酸-乙醇诱导SD大鼠胃损伤的预防效果,并通过组织观察和大鼠血清指标就巫山神茶对胃损伤的影响进行了研究.结果表明,巫山神茶提取物1 000 mg/kg处理比500 mg/kg和250 mg/kg处理显著降低了血清中IL-6和TNF-α炎症细胞因子水平(P

关 键 词:巫山神茶  SD大鼠  细胞因子  胃损伤  胃液分泌量  

Preventive effect of Wushan shencha on gastric injury in SD-rats
MU Xin;ZHAO Xin;LI Guijie;ZHANG Xue. Preventive effect of Wushan shencha on gastric injury in SD-rats[J]. Journal of Zhongkai University of Agriculture and Technology, 2014, 27(2): 57-59
Authors:MU Xin  ZHAO Xin  LI Guijie  ZHANG Xue
Affiliation:MU Xin;ZHAO Xin;LI Guijie;ZHANG Xue;Department of Biological and Chemical Engineering,Chongqing University of Education;
Abstract:SD rat model was used to study the HCl-Ethanol iuduced gastric injury preventive effect of Wushan shencha .The influence on gastric injury preventive effect of Wushan shencha was checked by microstructure and serum indexes .1 000 mg/kg concentration of Wushan shencha reduced the levels of serum proinflammatory cytokines of IL-6 and TNF-αcompared to the 500 and 250 mg/kg concentration samples ( P〈0.05 ) .The 1 000 mg/kg Wushan shencha administrated SD rats displayed the smallest gastric injury area (8.2 mm^2), it showed the best gastric injury inhibitory effect (42.3%).The gastric juice volume and pH of gastric juice of 1 000 mg/kg treated rats showed the levels close to the normal rats in 2.7 mL and 2.3.In this study, at the concentration of 1 000 mg/kg, Wushan shencha showed the best inhibitory effect on gastric injury .These results suggest that 1 000 mg/kg Wushan shencha treated SD rats showed best gastric injury preventive effect .
Keywords:Wushan shencha  SD-rat  cytokine  gastric injury  gastric secretion volume
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