动物抗菌肽诱导产生的方法及抗菌肽的应用前景

抗菌肽广泛存在于生物体内,具有理化性质稳定、广谱高效杀菌活性、不易产生耐药性以及在外界理化和生物因素诱导刺激下可增加其合成等特点。因此,抗菌肽具有广阔的开发应用前景,已成为国内外免疫学和分子生物学研究的热点。本文就动物抗菌肽的诱导方法、水产动物中诱导抗菌肽的研究实例进行了综述,并介绍了抗菌肽的应用前景与面临的问题。

Induction Methods of Antibacterial Peptides in Animals and Application Prospect of Antimicrobial Peptides

Antibacterial peptides exist widely in the organisms, which have some characteristics, such as stable physical and chemical properties, broad spectrum bactericidal activity and synthesis of the peptides in organisms can be increased by physical, chemical and biological factors. Because the bacteria are of little resistance to antibacterial peptides, antibacterial peptides show a good application prospect and have become a research focus in immunology and molecular biology. In this paper, induction methods of antibacterial peptides and the studies on aquatic animals are summarized, and the application prospect and the problems are also introduced.