| 一株野生毛头鬼伞子实体对小鼠的亚急性毒性试验 |
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| 引用本文： | 曹晋良,韩建荣. 一株野生毛头鬼伞子实体对小鼠的亚急性毒性试验[J]. 食用菌学报, 2017, 0(2): 71-74. DOI: 10.16488/j.cnki.1005-9873.2017.02.16 |
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| 作者姓名： | 曹晋良 韩建荣 |
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| 作者单位： | 山西大学生命科学学院,山西太原,030006 |
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| 基金项目： | 山西省煤基重点科技攻关项目(FT2014-03-15) |
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| 摘 要： | 以小鼠为受试动物评价一株野生毛头鬼伞(Coprinus comatus)菌株ZMM-3人工栽培子实体的食用安全性,结果在高、中、低(5000、500、50mg/kg·d)剂量组实验中小鼠全部健活,体征、体重、行为、外观、脏器系数、血液生理生化指标、脏器结构均无明显异常,表明供试毛头鬼伞子实体对小鼠没有亚急性毒性。
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| 关 键 词： | 野生毛头鬼伞 亚急性毒性 脏器结构 |
Evaluation of a Coprinus comatus Fruit Body for Sub-acute Toxicity in Mice |
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| CAO Jinliang,HAN Jianrong. Evaluation of a Coprinus comatus Fruit Body for Sub-acute Toxicity in Mice[J]. Acta Edulis Fungi, 2017, 0(2): 71-74. DOI: 10.16488/j.cnki.1005-9873.2017.02.16 |
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| Authors: | CAO Jinliang HAN Jianrong |
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| Abstract: | Organ coefficients (lung, kidney, heart, spleen, liver), hematological criteria and various biochemical parameters were monitored in mice administered 50, 500 and 5000 mg/kg·d of a powdered Coprinus comatus fruit body (designated ZMM-3) collected from the wild.No abnormal physical signs,changes in behavior, body weight, organ coefficients, and hematological and biochemical parameters were observed, indicating the absence of any obvious sub-acute toxicity. |
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| Keywords: | Coprinus comatus sub-acute toxicity organ coefficient |
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