马来亚豪猪中国亚种皮肤伤口无疤痕愈合能力的研究

[目的]研究马来亚豪猪中国亚种皮肤伤口无疤痕愈合方式。[方法]对马来亚豪猪中国亚种的耳部实施贯穿伤及撕裂伤,以7 d为节点拍照记录伤口愈合情况;运用石蜡切片、HE染色等方法对豪猪耳部伤口愈合进展进行组织学观察。[结果]撕裂伤口能够在63 d内以无疤痕的方式愈合,于再生区观察到新生的脂肪组织、真皮、表皮和丰富的毛囊。[结论]该研究结果有助于探明豪猪皮肤创伤无疤痕愈合的机理以及了解动物皮肤损伤修复的机制,可为治愈人的大面积皮肤创伤提供参考。

Observation of Scar-free Healing of Skin Wounds in Hystrix brachyura hodgsoni

[Objective]To characterize the scar-free healing of skin wounds in Hystrix brachyura hodgsoni. [Method]Penetrating and lacerating wounds in the ear skin of Hystrix brachyura hodgsoni were prepared. The healing processes of the skin wounds were observed and photographically recorded once every 7 days, and were histologically characterized by hematoxylin-eosin （HE） staining of paraffin sections. [Result]The lacerating wounds in the ear skin of Hystrix brachyura hodgsoni healed in a scar-free manner within 63 days, and regenerated adipose tissue, dermis, epidermis and abundant hair follicle were histologically observed. [Conclusion]The results of this study are helpful to explore the mechanism of scar-free healing of skin wounds in Hystrix brachyura hodgsoni and to understand the mechanism of animal skin repair, which may provide references for curing large-area skin wounds in human.