Assessment of nebulisation of sodium ceftiofur in the treatment of calves naturally infected with bovine respiratory disease |
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Authors: | Vivek Joshi V K Gupta U Dimri O R Vinodh Kumar D K Sharma A G Bhanuprakash |
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Institution: | 1.Division of Medicine,ICAR-Indian Veterinary Research Institute,Bareilly,India;2.Division of Epidemiology,ICAR-Indian Veterinary Research Institute,Bareilly,India |
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Abstract: | Twelve screened cases of bovine respiratory disease (BRD) in calves were enrolled. Six of the calves were treated intramuscularly with sodium ceftiofur (1 mg/kg), and six were treated with nebulised sodium ceftiofur (1 mg/kg). Comparative evaluation of the two therapeutic modalities was based on repetitive analysis of hematological profile of calves on days 0, 5, and 10 post-therapy. The mortality rate in the group of calves treated with the nebulised sodium ceftiofur was significantly (p?<?0.001) lower, and their clinical and hematological parameters returned to normal significantly (p?<?0.001) faster than in calves treated intramuscularly. Nebulisation of sodium ceftiofur is the most effective treatment in calves with BRD under field conditions. Nasal lavage fluid analysis indicating a high rise of neutrophil count and macrophages may be used as an alternative method to detect pulmonary inflammation in BRD-affected calves. |
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